Exosome Therapeutics for Regenerative Applications
ExTherea is a biotechnology company founded in Kanagawa, Japan. We are investigating exosomes - nano-sized particles which are released by cells - and their use in regenerative medicine.
Specifically, we are studying exosomes derived from oral mucosa - one of the tissues in the human body with the highest capacity of regeneration. The underlying research was performed at Karolinska Institutet and Tokyo Women's Medical University.
2020-08 ExTherea was one of the five awardees for the "World Without Disease" grant from Takeda Pharmaceuticals, out of 79 applicants. The grant provides research funding (10M yen / year) and lab space for three years. Press release in Japanese. In this project we aim to develop an "exosome-loaded nasal spray" as a treatment for neurodegenerative disorders.
2020-02 ExTherea laboratory in Shonan iPark officially opened.
2019-12 ExTherea was featured in Nikkei Biotech - one of Japan's biggest journal specializing on biotechnology (link)
2019-11 ExTherea Inc. was registered in Kanagawa prefecture, Japan.
2020-08 Awardee in Takeda and Johnson and Johnson's "World Without Disease" program, providing funding and lab space for three years.
2019-04 Sebastian Sjoqvist (co-founder and CSO of ExTherea) was selected for Young Investigator Award by International Society for Extracellular Vesicles
2019-03 ExTherea was one of finalist in Blockbuster TOKYO accelerator program.
2019-02 ExTherea received first funding from the Blockbuster TOKYO program.
2018-08 ExTherea was finalist in Tissue Engineering and Regenerative Medicine International Society World Congress' Business Plan Competition
2020-12 "Extracellular Vesicle Therapeutics in Regenerative Medicine", Imafuku et al, Advances in Experimental Medicine and Biology [Book chapter]
2019-09 "Isolation and Characterization of Extracellular Vesicles from Keratinocyte Cultures", Sjöqvist et al, Methods Mol Bio [Book chapter]
2019-05 "Oral keratinocyte-derived exosomes regulate proliferation of fibroblasts and epithelial cells", Sjöqvist et al, Biochem Biophys Res Commun. [IF 2.6]
2019-01 "Exosomes derived from clinical-grade oral mucosal epithelial cell sheets promote wound healing", Sjöqvist et al, Journal of Extracellular Vesicles [IF 15]
We can assist your company or research team with exosome related research, at very competitive prices.
Consultation of study design
Exosome isolation and characterization
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